What makes a drug to be hepatotoxic?: how new technologies can help to better understand the phenomena
José V. Castell. Unit for Experimental Hepatology. Research Institute of the University Hospital La Fe. Valencia. ESP

• Allan Boobis (Food Chem Toxicol)
  
• Walgang Dekant (Toxicol Letters)
  
• Jan G Hengstler (Arch Toxicol)
  
• Roger O McClellan (Crit Rev Toxicol)
  
• Philip Wexler (NIH/NLM)
  

TRISK. Risk Assessor training: ensuring availability of highly qualified professionals (Informativew session)
Corrado Galli and Takis Daskaleros. TRISK project.

• Welcome & General Overview of TRISK - Corrado L. Galli
• Fundamentals and key aspects of TRISK - Angelo Moretto
  
• Accreditation pros and cons - Helen Hakansson
  
• Risk assessment training lessons learnt - Carmen  Estevan  (TRISK trainee)
  
• The reaction of industry stakeholders - Giuseppe Malinverno
  
• A scientific support in risk assessment dissemination: EFSA Journal - Carola Sondermann

The laboratory animal : a key player in toxicological sciences (Sponsored by Association for Assessment and Accreditation of Laboratory Animal Care, AAALAC International)

AAALAC International: quality science and animal welfare together in an accreditation scheme
Javier Guillén. Senior Director and Director of European Activities. AAALAC International

Benefits in Toxicology from peer reviews of animal care and use programs
Peter Clausing. Senior Toxicologist. Council on Accreditation AAALAC International

Informative Workshop Fron Carcinogenicity to Metabolomic – Challances in Regulatory Toxicology process
(Sponsored by BASF)

Metabolomics: A tool for early identification of toxicological effects and an opportunity for biology based chemical grouping under REACH (Bennard. van Ravenzwaay)

Mode of action: CAR-mediated rodent-specific hepatocarcinogenicity (Naveed Honarvar)

Pathology Working Group: A scientific solution for conflicting pathological datasets (Sibylle Gröters)

Label-Free Testing for Embryotoxicity, and Hepatic Cell and Cardiomyocyte Cytotoxicity
(Sponsored by ROCHE)

Identification of embryotoxic effects of the marine biotoxin okadaic acid using different murine embryonic stem cells
Alfonso Lampen. Department Food Safety. Federal Institute for Risk Assessment. Berlin

Screening of Cardiotoxic and Pro-Ayythmic Compounds Using Stem Cell-Derived Cardiomyocytes with the xCELLigence RTCA Cardio System
Yama A. Abassi, ACEA, Cell Biology and Assay Development

Global impact of 3’Rs on regulatory processes: sharing experiences and future trends.
Organised by REMA (Spanish Platform on Alternatives) with the participation of experts from REMA, ECOPA, ECVAM, JACVAM, CAAT, BASF, Ferrer International
Chair: Argelia Castaño. (REMA Prtesident, I. S. Carlos III, Madrid).

Speakers: 
Adela Lopez de Cerain (ECOPA President, Universidad de Navarra),
Hajime Kojima (JaCVAM)
Pilar Prieto (ECVAM)
Thomas Hartung (CAAT)
Domingo Gargallo, Toxicology and Safety Pharmacology. Ferrer International
Robert Landsiedel. BASF Product Safety.- Experimental Toxicology and Ecology

Accomplishments and Challenges in Global Chemicals Policy
(With the collaboration of experts from the US NLM, UN, WHO OECD, OpenTox and Eco Conseil)
Chair: Philip Wexler, US National Library of Medicine. USA

Advancing toxicology through a more strategic approach to international chemicals management
Lesley Onyon, United Nations Environment Programme
Carolyn Vickers, World Health Organization

A European Chemicals Agency Perspective
David Bell, European Chemicals Agency (ECHA)

Satisfying REACH Requirements in Predictive Toxicology
Barry Hardy, OpenTox Project Coordinator.

OECD Chemicals Programme and Test Guidelines
Laurence Musset, Test Guidelines Programme, OECD
Hitoshi Someya, Environment Directorate, OECD.

Globally Harmonised System for Classification and Labeling
Jan van der Kolk, Eco Conseil

To appreciate the context of toxicology in the present, and plan for its future, it is critical that we understand its history.  The International Congress of Toxicology -XII is pleased to present the Toxicology History Room (THR), an exhibit of posters providing a perspective on the history of the science of toxicology and its relation to society.  Subjects will include noteworthy toxicologists and their contributions through the ages, organizations that have played a key role in scientific and regulatory affairs, chemicals which have been controversial, major toxic accidents, and more.  We invite you to browse this selection of displays and suggest more for the expansion of the THR at future meetings.  Though Isaac Newton did not invent the following phrase, it gained in popularity after he used it in a letter in the 17th century, in reference to some of his own accomplishments:  “If I have seen a little further it is by standing on the shoulders of Giants.”
(Note: the contents of the posters are responsibility of their authors)