20 July 21 July 22 July 23 July


Simposia 21 July




21 July

10:30

SY09

Individual susceptibility to environmental and occupation exposure
Nursen Basaran. Hacettepe University Faculty of Pharmacy, Ankara. TR

 

 

SY09-1

Effect of genetic and environmental factors on biomarkers of exposure
Hermann Autrup. Univ. of Aarhus, Aarhus, Denmark.. DNK

 

 

SY09-2

Modulation of arseniasis risk by host factors in a multiethnic village
Jian-Hua Shen
. Shanghai Institutes of Biological Sciences, Chinese Acad.Sc., Shanghai,. CHN

 

 

SY09-3

Human bladder cancer and individual susceptibility factors
Miriam Angeli-Greaves. Univ. of Vernezuela, Caracas, Venezuela. VEN

 

 

SY09-4

Factors of individual susceptibility to benzene: state of the art
Robert Snyder. EOHSI, Rutgers University, Piscataway, NJ, USA.. USA

 

 

SY09-5

Application of DNA-chip based techniques in occupational studies
Jan G. Hengstler. IfADo. Dortmund, Germany.. DEU


21 July

10:30

SY10

Endocrine disrupters: effects on reproduction and development
Anunciación Lafuente. Lab. of Toxicology, University of Vigo. ESP

 

 

SY10-1

Steroid hormone receptors and metabolism in endocrine disruption.
Sari Mäkelä. Functional Foods Forum. University of Turku. FIN

 

 

SY10-2

Retinoid receptors and metabolism in endocrine disruption.
Helen Håkansson. The Institute of Environmental Medicine, Karolinska Institute, Stockholm. SWE

 

 

SY10-3

Reprogramming of DNA methylation during mammalian development and impact of Endocrine Disruptors.
Michael Weber. Institute of Molecular Genetics CNRS,. FRA

 

 

SY10-4

Criteria for the interpretation of reproductive and endocrine effects detected in regulatory guideline studies.
Roland Solecki. Bfr, Berlin,. DEU

 

 

SY10-5

Delineation of Persistent Organic Pollutant effects in human: cellular and clinical studies
Robert Barouki. Université René Descartes. Paris. FRA


21 July

10:30

SY11

Genotoxicity testing: for impurities in drugs.
Ricard Marcos. Autonomous University of Barcelona

 

 

SY11-1

Genotoxicity assessment in early drug development: identification, new models and strategies
Jacky Van Gompel. Genotoxicology and in vitro toxicology of J&J Pharma. BEL

 

 

SY11-2

Genotoxicological qualification of impurities in the pharmaceutical industry
Michelle Kenyon. Genotoxicologist at Pfizer, Groton. USA

 

 

SY11-3

Genotoxicity testing of pharmaceuticals: An update on changing regulatory guidances
Peter Kasper. German Regulatory Agency Bfarm. DEU

 

 

SY11-4

Future approaches to genotoxicity testing for drugs and impurities.
David Tweats. Genetic toxicology, Sweansea University, Wales. GBR

 

 

SY11-5

Threshold for Toxicological Concern (TTC) and impurities.
Lutz Müller. Hoffmann-La Roche, Basel. CHE


21 July

10:30

SY12

Drugs of Abuse-The things you didn’t know
Donna Seger. Vanderbilt University Medical Center. Nashville TN. USA

 

 

SY12-1

Cocaine-Why so Lethal?
Robert Hoffman. New York City Poison Control Center. USA

 

 

SY12-2

Cannabis acute and chronic effects-The Dutch Experience
Irma de Vries. National Poisons Information Centre, Bilthoven,. NLD

 

 

SY12-3

GHB and other submission agents. Clinical and legal implications
Santiago Nogué. Unit of Clinical Toxicology. Clinic Hospital Barcelona. ESP

 

 

SY12-4

Neuroadaptation and Drugs of Abuse or How Drugs  Change your Brain
Donna Seger. Vanderbilt University Medical Center. Nashville TN. USA

 

 

SY12-5

New emerging designer drugs
Paul Dargan. Guy’s and St. Thomas Poisons Unit. London.. GBR


21 July

16:30

SY13

Risk Assessment of Herbal Medicines and Botanical Supplements (similar, but still different!)
Olavi Pelkonen. Dept Pharmacol & Toxicol, University of Oulu. FIN

 

 

SY13-1

Herbals and botanicals in the grey area between medicines and nutrition: scientific and regulatory challenges
Gert Laekeman. Katolieke Universiteit Leuven. Leuven,. BEL

 

 

SY13-2

A huge number of mixtures and substances: how to deal with them?
Mª da Graça Campos. Faculty of Pharmacy. Universidade de Coimbra Azinhaga de Sta Comba Coimbra

 

 

SY13-3

Standardized Evaluation of TCM drug safety and its safe use in China
Zu-Guang Ye. State Research Center for R&D of TCM Multiingredient drug. Chinese Academy of TCM. Beijing. CHN

 

 

SY13-4

Compability risks between drugs and herbal medicines or botanical supplements
Ashim K. Mitra. School of Pharmacy. University of Missouri-Kansas City. USA



21 July

16:30

SY14

Glia-Neuron Interactions in Neurotoxicology
Marina Guizzetti. University of Washington, Seattle, WA. USA

 

 

SY14-1

Proinflammatory cytokines, glutamatergic system and neurotoxicity.
Barbara Viviani. Universita’ degli Studi di Milano. ITA

 

 

SY14-2

Ethanol activates  IL-1RI/TLR4 in glial cells and induces neuroinflammation
Consuelo Guerri. Centro de Investigación Príncipe Felipe, Valencia. ESP

 

 

SY14-3

Chaperone deficiency in Pb-exposed glia: links to neurodegenerative diseases
Evelyn Tiffany-Castiglioni. Texas A&M University. College Station TX. USA

 

 

SY14-4

Fetal Alcohol Spectrum Disorders: inhibition of astrocyte release of extracellular matrix proteins and neuritogenesis.
Marina Guizzetti. University of Washington, Seattle, WA. USA


21 July

16:30

SY15

Toxicity and risk assessment of heat-treatment formed products
Wolfgang Dekant. Department of Toxicology, University of Würzburg,. DEU

SY15-1

Heat-treatment induced toxicant in food: Needs for health risk assessment
Wolfgang Dekant
. Department of Toxicology, University of Würzburg,. DEU

SY15-2

Risk assessment of chemicals formed by heat processing of food
Angelika Tritscher
. WHO Joint Secretary to JECFA and JMPR, Geneva. WHO

SY15-3

Role of genetic and epigenetic mechanisms in furan toxicity
Kevin Chipman
. University of Birminghamj. GBR

21 July

16:30

SY16

Integration of genomics, proteomics and metabolomics technologies in drug safety assessment
Joan-Albert Vericat. jvericat@noscira.com.

 

 

SY16-1

Integration of X-Omics data in the decision making process in Drug Development. The Melius Consortium.
Joan Vericat. . Noscira. Madrid. ESP

 

 

SY16-2

Integration of genomics, proteomics and metabolomics technologies in drug safety assessment: the need for collaboration and external funding
Phil Hewitt.
Merck KGaA, Darmstadt. DEU

 

 

SY16-3

The use of X-Omics in regulatory studies
Federico Goodsaid.  U.S. Food and Drug Administration, Silver Spring, MD, USA

 

 

SY16-4

EMEA’s position in the use of X-Omics in regulatory studies
Dominique Masset
, Toxicology Department, DEMEB, FRA